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2,5-Dimethyl-pyrazine 1,4-dioxide.

ABSTRACT: The title compound, C(6)H(8)N(2)O(2), was prepared from 2,5-dimethyl-pyrazine, acetic acid, and hydrogen peroxide. The 2,5-dimethyl-pyrazine 1,4-dioxide mol-ecule is located on an inversion center. π-π inter-actions between neighboring 2,5-dimethyl-pyrazine 1,4-dioxide mol-ecules are observed with an inter-planar distance of 3.191 Å. Each 2,5-dimethyl-pyrazine 1,4-dioxide mol-ecule is linked to four neighboring N-oxide mol-ecules through C-H⋯O hydrogen-bonding inter-actions, forming two-dimensional layers.

SUBMITTER: Brown CJ

PROVIDER: S-EPMC2971924 | biostudies-literature |

REPOSITORIES: biostudies-literature

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catena-Poly[[[diaqua-bis(8-hydroxy-quinoline N-oxide-?O)cobalt(II)]-?-2,5-dimethyl-pyrazine 1,4-dioxide-?O:O] bis-(perchlorate)].

Project description:In the title complex, {[Co(C(6)H(8)N(2)O(2))(C(9)H(7)NO(2))(H(2)O)(2)](ClO(4))(2)}(n), the Co(II) ion lies on an inversion centre and is coordinated in a slightly distorted octa-hedral environment. The 2,5-dimethyl-pyrazine 1,4-dioxide ligand, which also lies on an inversion center, acts as a bridging ligand, linking symmetry-related Co(II) ions [Co?Co = 8.669?(3)?Å] and forming one-dimensional chains along the b axis. In the crystal structure, these chains are linked by inter-molecular aqua-perchlorate O-H?O hydrogen bonds, forming two-dimensional layers which are in turn connected into a three-dimensional network via ?-? stacking inter-actions between quinoline rings, with a centroid-centroid distance of 3.580?(3)?Å. An intermolecular O-H?Cl inter-action is also present.

| S-EPMC2984066 | biostudies-literature

2-Methyl-pyrazine 1,4-dioxide.

Project description:The title compound, C(5)H(6)N(2)O(2), was prepared from 2-methyl-pyrazine, acetic acid and hydrogen peroxide. In the crystal, ?-? stacking inter-actions between neighboring mol-ecules are observed, with a centroid-centroid distance of 3.7370?Å, an inter-planar distance of 3.167?Å, and a slippage of 1.984?Å. Each mol-ecule is linked to four neighbors through C-H?O hydrogen-bonding inter-actions, forming one-dimensional ribbons.

| S-EPMC2971871 | biostudies-other

1,4-Bis(dimethyl-silyl)-2,5-diphenyl-benzene.

Project description:The mol-ecule of the title compound, C(22)H(26)Si(2), is centrosymmetric. The dihedral angle between the central benzene ring and its phenyl substituents is 67.7?(2)°. The crystal packing is stabilized by van der Waals forces.

| S-EPMC2983822 | biostudies-literature

2,5-Bis[4-(dimethyl-amino)-phen-yl]-3,6-dimethyl-pyrazine.

Project description:The title compound, C(22)H(26)N(4), was prepared from p-dimethyl-amino-propiophenone in six steps. The mol-ecule has no crystallographic symmetry. The dihedral angles between the pyrazine ring and the phenyl rings are 35.81?(6) and 37.11?(8)°. The dimethyl-amino groups are essentially planar (sum of the bond angles at N = 359.3 and 359.9°) and nearly coplanar with the adjacent aromatic ring [dihedral angles = 5.54?(11) and 7.40?(3)°]. This effect and the short aniline C-N bonds can be rationalised in terms of charge transfer from the amino groups to the central pyrazine ring.

| S-EPMC3120404 | biostudies-other

Bis(dimethyl-ammonium) 2,5-dihy-droxy-benzene-1,4-disulfonate.

Project description:In the crystal of the title salt, 2C(2)H(8)N(+)·C(6)H(4)O(8)S(2) (2-), the anion lies on a center of inversion. The dimethyl-ammonium cation forms one N-H?O hydrogen bond and another bifurcated N-H?O hydrogen bond. The hy-droxy group links with the sulfonyl group via an inter-molecular O-H?O hydrogen bond. These N-H?O and O-H?O hydrogen bonds generate a three-dimensional network.

| S-EPMC3275289 | biostudies-literature

Hexaaqua-copper(II) bis-(tetra-fluorido-borate)-pyrazine 1,4-dioxide (1/3).

Project description:The crystal structure of the title compound, [Cu(H2O)6](BF4)2·3C4H4N2O2, comprises discrete [Cu(H2O)6](2+) cations and BF4 (-) anions along with three equivalents of pyrazine 1,4-dioxide (pzdo). The hexa-aqua-copper(II) ion and all three pzdo mol-ecules lie about crystallographic inversion centers. The lattice is supported by an extensive hydrogen-bonding network. O-H?O hydrogen bonding between the [Cu(H2O)6](2+) and pzdo units creates a pseudo-hexa-gonal lattice parallel to the bc plane. The BF4 (-) anions lie in the voids of that lattice, held in place by O-H?F hydrogen bonds, and also generate BF4 (-)-pzdo-BF4 (-)-pzdo stacks via short F?N contacts [2.866?(3)-3.283?(4)?Å].

| S-EPMC3629502 | biostudies-literature

1,4-Bis(1,1-dimethyl-prop-yl)-2,5-dimeth-oxy-benzene.

Project description:The title compound, C(18)H(30)O(2), was prepared by Friedel-Crafts alkyl-ation of 1,4-dimeth-oxy-benzene with 2-methyl-2-butanol. The complete mol-ecule is generated by the application of a crystallographic centre of inversion. The two meth-oxy groups are oriented in the same plane of the aromatic ring [C-C-O-C torsion angle = 9.14?(16)°]. While one methyl group of the tert-pentyl substituent is coplanar with the benzene ring [C-C-C-C = 0.45?(15)°] and lies towards the less-hindered H atom, the other methyl and ethyl groups are directed to either side of the benzene ring [C-C-C-C torsion angles = 118.78?(12) and 59.11?(14)°, respectively]. In the crystal, the hydro-phobic mol-ecules pack to form a brick-wall-like architecture.

| S-EPMC3201239 | biostudies-literature

(2S*,5R*)-2,5-Dimethyl-1,4-bis-(pyridin-2-ylmeth-yl)piperazine.

Project description:The title compound, C18H24N4, resides on a crystallographic inversion centre, so that the asymmetric unit comprises one half-mol-ecule. The piperazine ring adopts a chair conformation, with the mean planes of the two equatorial pyridine rings parallel to each other and separated by 2.54?(3)?Å. No classical hydrogen bonds are observed.

| S-EPMC3770377 | biostudies-literature

1-(2,5-Dimethyl-phen-yl)piperazine-1,4-diium tetra-chloridozincate monohydrate.

Project description:In the title compound, (C(12)H(20)N(2))[ZnCl(4)]·H(2)O, the two piperazine N atoms are protonated and the [ZnCl(4)](2-) anions adopt a slightly distorted tetra-hedral configuration. In the crystal, O-H⋯Cl hydrogen bonds link the tetra-chloridozincate anions and the water mol-ecules into corrugated inorganic chains parallel to [010]. The crystal structure is stabilized by N-H⋯Cl, N-H⋯O and O-H⋯Cl hydrogen bonds, with the N-H hydrogen bond originating from one of the two N atoms being trifurcated.

| S-EPMC3099933 | biostudies-literature

Diethyl trans-2,5-bis-(4-methoxy-benzyl-sulfan-yl)-1,4-dimethyl-3,6-dioxopiperazine-2,5-carboxyl-ate.

Project description:The title compound, C(28)H(34)N(2)O(8)S(2), was synthesized as part of a project to develop synthetic routes to analogues of sporidesmins, a class of secondary metabolite produced by the filamentous fungi Chaetomium and Pithomyces sp. The complete molecule is generated by crystallographic inversion symmetry: the methoxy group is essentially coplanar with the benzene ring to which it is bonded, a mean plane fitted through the non-H atoms of the aromatic ring and the meth-oxy group having an r.m.s. deviation of 0.0140?Å. Similarly, the ester group is also essentially planar (r.m.s. deviation of a plane fitted through all non-H atoms is 0.0101?Å). There is only one independent C-H?O inter-action, which links together adjacent mol-ecules into a two-dimensional sheet in the bc plane.

| S-EPMC2969498 | biostudies-literature

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