Nuclear hormone receptors in parasitic helminths.
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ABSTRACT:
SUBMITTER: Wu W
PROVIDER: S-EPMC2974807 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Publications
Nuclear hormone receptors in parasitic helminths.
Wu Wenjie W LoVerde Philip T PT
Molecular and cellular endocrinology 20100626 1-2
Nuclear receptors (NRs) belong to a large protein superfamily that are important transcriptional modulators in metazoans. Parasitic helminths include parasitic worms from the Lophotrochozoa (Platyhelminths) and Ecdysozoa (Nematoda). NRs in parasitic helminths diverged into two different evolutionary lineages. NRs in parasitic Platyhelminths have orthologues in Deuterostomes, in arthropods or both with a feature of extensive gene loss and gene duplication within different gene groups. NRs in para ...[more]
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