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(4S,5S)-2-(4-Chloro-phen-yl)-1,3-dioxolane-4,5-dicarboxamide.

ABSTRACT: The title compound, C(11)H(11)ClN(2)O(4), is an important inter-mediate for the preparation of platinum anti-cancer drugs. The dioxolane ring adopts a twist conformation with an equatorially attached chloro-phenyl substituent. In the crystal structure, mol-ecules are linked into a two-dimensional network parallel to (001) by N-H?O and C-H?O hydrogen bonds.

SUBMITTER: Wang DC

PROVIDER: S-EPMC2977328 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature

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(4S,5S)-2-(4-Chloro-phen-yl)-1,3-dioxolane-4,5-dicarboxamide.

Wang De-Cai DC Bai Jing J Xu Wei W Gai Tao T Liu Hua-Quan HQ

Acta crystallographica. Section E, Structure reports online 20090722 Pt 8

The title compound, C(11)H(11)ClN(2)O(4), is an important inter-mediate for the preparation of platinum anti-cancer drugs. The dioxolane ring adopts a twist conformation with an equatorially attached chloro-phenyl substituent. In the crystal structure, mol-ecules are linked into a two-dimensional network parallel to (001) by N-H⋯O and C-H⋯O hydrogen bonds. ...[more]

PMID: 21583638

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