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N-(2,5-Dimethoxy-phen-yl)-4-nitro-benzene-sulfonamide.

ABSTRACT: The title compound, C(14)H(14)N(2)O(6)S, is an inter-mediate for the synthesis of ?-3-adrenergic receptor agonists. The two meth-oxy groups are approximately coplanar with the attached benzene ring [C-O-C-C = -2.7?(4) and 9.4?(4)°]. The dihedral angle between the two aromatic rings is 67.16?(12)°. An intra-molecular N-H?O hydrogen bond is observed. In the crystal, mol-ecules are linked into chains along the c axis by C-H?O hydrogen bonds.

SUBMITTER: Zhang GY

PROVIDER: S-EPMC2977360 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature

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N-(2,5-Dimethoxy-phen-yl)-4-nitro-benzene-sulfonamide.

Zhang Guo-Yao GY Qian Shan S Li Xiao-Cen XC Wu Yong Y

Acta crystallographica. Section E, Structure reports online 20090722 Pt 8

The title compound, C(14)H(14)N(2)O(6)S, is an inter-mediate for the synthesis of β-3-adrenergic receptor agonists. The two meth-oxy groups are approximately coplanar with the attached benzene ring [C-O-C-C = -2.7 (4) and 9.4 (4)°]. The dihedral angle between the two aromatic rings is 67.16 (12)°. An intra-molecular N-H⋯O hydrogen bond is observed. In the crystal, mol-ecules are linked into chains along the c axis by C-H⋯O hydrogen bonds. ...[more]

PMID: 21583621

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