Ontology highlight
ABSTRACT:
SUBMITTER: Liu WC
PROVIDER: S-EPMC2977862 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Liu Wen-Chun WC Lin Shih-Chang SC Yu Yen-Ling YL Chu Ching-Liang CL Wu Suh-Chin SC
Journal of virology 20100915 22
Since dendritic cells may play a key role in defense against influenza virus infection, we examined the effects of recombinant hemagglutinin (HA) proteins derived from mouse-adapted H1N1 (A/WSN/1933), swine-origin 2009 pandemic H1N1 (A/Texas/05/2009), and highly pathogenic avian influenza H5N1 (A/Thailand/KAN-1/2004) viruses on mouse myeloid dendritic cells (mDCs). The results reveal that tumor necrosis factor alpha (TNF-α), interleukin-12 (IL-12) p70, and major histocompatibility complex class ...[more]