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(E)-N'-(2,4,6-Trimethyl-benzyl-idene)isonicotinohydrazide.

ABSTRACT: The title isoniazid derivative, C(16)H(17)N(3)O, exists in an E configuration with respect to the Schiff base C=N bond. The pyridine ring is essentially planar [maximum deviation = 0.009?(3)?Å]. The mean plane through the hydrazide unit forms dihedral angles of 38.38?(16) and 39.42?(16)°, respectively, with the pyridine and benzene rings. In the crystal structure, symmetry-related mol-ecules are linked via inter-molecular N-H?O hydrogen bonds into chains along [100]. The crystal structure is further stabilized by weak inter-molecular C-H?? inter-actions.

SUBMITTER: Naveenkumar HS

PROVIDER: S-EPMC2979577 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature

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(E)-N'-(2,4,6-Trimethyl-benzyl-idene)isonicotinohydrazide.

Naveenkumar H S HS Sadikun Amirin A Ibrahim Pazilah P Goh Jia Hao JH Fun Hoong-Kun HK

Acta crystallographica. Section E, Structure reports online 20100529 Pt 6

The title isoniazid derivative, C(16)H(17)N(3)O, exists in an E configuration with respect to the Schiff base C=N bond. The pyridine ring is essentially planar [maximum deviation = 0.009 (3) Å]. The mean plane through the hydrazide unit forms dihedral angles of 38.38 (16) and 39.42 (16)°, respectively, with the pyridine and benzene rings. In the crystal structure, symmetry-related mol-ecules are linked via inter-molecular N-H⋯O hydrogen bonds into chains along [100]. The crystal structure is fur ...[more]

PMID: 21579555

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