Alkaline phosphatase and percentage body fat predict circulating C-reactive protein in premenopausal women.
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ABSTRACT:
SUBMITTER: Nayeem F
PROVIDER: S-EPMC2981667 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
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Alkaline phosphatase and percentage body fat predict circulating C-reactive protein in premenopausal women.
Nayeem Fatima F Anderson Karl E KE Nagamani Manubai M Grady James J JJ Lu Lee-Jane W LJ
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100929 8
C-reactive protein (CRP) is considered a marker of inflammation, which is a risk factor for many chronic diseases. However, determinants of CRP remain unclear and were studied in a strictly defined cohort of healthy premenopausal women (n=233) using multiple regression models. Independent predictors of serum CRP (model R(2)=0.59) were percentage body fat, serum alkaline phosphatase (ALP), sex hormone-binding globulin and white blood cell count. The close association between CRP and ALP suggests ...[more]
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