Ontology highlight
ABSTRACT:
SUBMITTER: Gajda MJ
PROVIDER: S-EPMC2982159 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Bioinformatics (Oxford, England) 20101017 23
<h4>Summary</h4>Automatic methods for macromolecular structure prediction (fold recognition, de novo folding and docking programs) produce large sets of alternative models. These large model sets often include many native-like structures, which are often scored as false positives. Such native-like models can be more easily identified based on data from experimental analyses used as structural restraints (e.g. identification of nearby residues by cross-linking, chemical modification, site-directe ...[more]