Proton channel models filling the gap between experimental data and the structural rationale.
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ABSTRACT:
SUBMITTER: Pupo A
PROVIDER: S-EPMC4203746 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
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Proton channel models filling the gap between experimental data and the structural rationale.
Pupo Amaury A Baez-Nieto David D Martínez Agustín A Latorre Ramón R González Carlos C
Channels (Austin, Tex.) 20140101 3
Voltage-gated proton channels are integral membrane proteins with the capacity to permeate elementary particles in a voltage- and pH-dependent manner. These proteins have been found in several species and are involved in various physiological processes. Although their primary topology is known, lack of details regarding their structures in the open conformation has limited analyses toward a deeper understanding of the molecular determinants of their function and regulation. Consequently, the fun ...[more]
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