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1,3,5-Triaza-adamantan-7-amine.

ABSTRACT: The title compound, C(7)H(14)N(4), represents the first structurally characterized, isolated triaza-adamantane. In the crystal structure, weak inter-molecular N-H?N hydrogen bonds link the mol-ecules into columns about the crystallographic fourfold axis.

SUBMITTER: Thomson J

PROVIDER: S-EPMC2983202 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature

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1,3,5-Triaza-adamantan-7-amine.

Thomson Jaclyn J Chisholm Danielle M DM Oliver Allen G AG McIndoe J Scott JS

Acta crystallographica. Section E, Structure reports online 20100925 Pt 10

The title compound, C(7)H(14)N(4), represents the first structurally characterized, isolated triaza-adamantane. In the crystal structure, weak inter-molecular N-H⋯N hydrogen bonds link the mol-ecules into columns about the crystallographic fourfold axis. ...[more]

PMID: 21587609

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Enzymatic Approach to the Synthesis of Enantiomerically Pure Hydroxy Derivatives of 1,3,5-Triaza-7-phosphaadamantane.

Project description:A series of enantiomerically pure derivatives of 6-(1-hydroxyalkyl)-1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane 5 were successfully synthesized for the first time. A series of hydrolytic enzymes was applied in a stereoselective acetylation performed under kinetic resolution conditions. Although the secondary alcohols: α-aryl-hydroxymethyl-PTA (phosphines) 5b-d', PTA-oxides 8b-d', and PTA-sulfides 9b-d' were found to be totally unreactive in the presence of all the enzymes and various conditions applied, the primary alcohols, i.e., the hydroxymethyl derivatives PTA oxide 8a and PTA sulfide 9a, were successfully resolved into enantiomers with moderate to good enantioselectivity (up to 95%). The absolute configurations of the products were determined by an X-ray analysis and chemical correlation.

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1,3,5-Triaza-7-Phosphaadamantane (PTA) as a 31P NMR Probe for Organometallic Transition Metal Complexes in Solution.

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Project description:In the title compound, C(9)H(9)N(5)S, the pyridyl and triazine rings make a dihedral angle of 4.8?(2)°. In the crystal, adjacent mol-ecules are bridged by an N-H?N hydrogen bond, forming a helical chain running along the b axis.

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4-Chloro-N-methyl-6-(morpholin-4-yl)-N-phenyl-1,3,5-triazin-2-amine.

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