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N-Benzyl-2-(3-chloro-4-hy-droxy-phen-yl)acetamide.

ABSTRACT: The title compound, C(15)H(14)ClNO(2), was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hy-droxy-phen-yl)acetamide. It crystallizes as non-planar discrete mol-ecules [the peripheral 3-chloro-4-hy-droxy-phenyl and benzyl groups are twisted out of the plane of the central acetamide group, with N-C-C-C and C-C-C-C torsion angles of -58.8 (3) and 65.0 (2)°, respectively] linked by inter-molecular N-H⋯O and O-H⋯O hydrogen bonds.

SUBMITTER: Davis RA

PROVIDER: S-EPMC2983291 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature

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N-Benzyl-2-(3-chloro-4-hy-droxy-phen-yl)acetamide.

Davis Rohan A RA Healy Peter C PC

Acta crystallographica. Section E, Structure reports online 20100908 Pt 10

The title compound, C(15)H(14)ClNO(2), was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hy-droxy-phen-yl)acetamide. It crystallizes as non-planar discrete mol-ecules [the peripheral 3-chloro-4-hy-droxy-phenyl and benzyl groups are twisted out of the plane of the central acetamide group, with N-C-C-C and C-C-C-C torsion angles of -58.8 (3) and 65.0 (2)°, respectively] linked by inter-molecular N-H⋯O and O-H⋯O hydrogen bonds ...[more]

PMID: 21587515

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