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Dimethyl 1,4-dihydro-4-(4-methoxy-phen-yl)-2,6-dimethyl-pyridine-3,5-dicarboxyl-ate.

ABSTRACT: In the title compound, C(18)H(21)NO(5), the dihydro-pyridine ring adopts a flattened-boat conformation and its planar part forms a dihedral angle of 84.60?(2)° with the benzene ring. In the crystal, inter-molecular N-H?O and C-H?O hydrogen bonds result in the formation of zigzag layers parallel to (001). These layers are inter-connected via C-H?? inter-actions.

SUBMITTER: Loh WS

PROVIDER: S-EPMC2983583 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature

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Dimethyl 1,4-dihydro-4-(4-methoxy-phen-yl)-2,6-dimethyl-pyridine-3,5-dicarboxyl-ate.

Loh Wan-Sin WS Fun Hoong-Kun HK Reddy B Palakshi BP Vijayakumar V V Sarveswari S S

Acta crystallographica. Section E, Structure reports online 20100213 Pt 3

In the title compound, C(18)H(21)NO(5), the dihydro-pyridine ring adopts a flattened-boat conformation and its planar part forms a dihedral angle of 84.60 (2)° with the benzene ring. In the crystal, inter-molecular N-H⋯O and C-H⋯O hydrogen bonds result in the formation of zigzag layers parallel to (001). These layers are inter-connected via C-H⋯π inter-actions. ...[more]

PMID: 21580352

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Dimethyl 2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate.

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Project description:The title mol-ecule, C(19)H(23)NO(4), was synthesized by the reaction of benzaldehyde, ethyl acetoacetate and NH(4)HCO(3). The dihydro-pyridine ring adopts a flattened boat conformation and the plane of the base of the boat forms a dihedral angle of 88.78 (9)° with the phenyl ring. The packing is stabilized by strong inter-molecular N-H⋯O and weak inter-molecular C-H⋯O hydrogen bonds.

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Project description:The title compound, C(21)H(26)N(2)O(5), was unexpectedly obtained as a by-product in the reaction of ethyl acetoacetate, 4-acetamido-benzaldehyde and urea under microwave irradiation. The dihydro-pyridine ring assumes a flattened boat conformation. Inter-molecular N-H⋯O and weak C-H⋯O hydrogen bonding occurs in the crystal.

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