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Dimethyl 4-(4-hy-droxy-phen-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate.

ABSTRACT: The title mol-ecule, C(17)H(19)NO(5), was prepared by a Hantzsch dihydro-pyridine synthesis from 4-hy-droxy-benzaldehyde, methyl acetoacetate and NH(4)HCO(3). In the mol-ecular structure of the title compound, the dihydro-pyridine ring adopts a flattened boat conformation and the plane of the base of the boat forms a dihedral angle of 80.8?(2)° with the aromatic six-membered ring. The packing is stabilized by strong inter-molecular N-H?O(carbon-yl), O(hydrox-y)-H?O(carbon-yl) and weak intra-molecular C-H?O hydrogen bonds.

SUBMITTER: Zhang CH

PROVIDER: S-EPMC3200733 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature

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Dimethyl 4-(4-hy-droxy-phen-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate.

Zhang Chun-Hua CH Zhao Jing-Min JM Chen Bao-Guo BG

Acta crystallographica. Section E, Structure reports online 20110817 Pt 9

The title mol-ecule, C(17)H(19)NO(5), was prepared by a Hantzsch dihydro-pyridine synthesis from 4-hy-droxy-benzaldehyde, methyl acetoacetate and NH(4)HCO(3). In the mol-ecular structure of the title compound, the dihydro-pyridine ring adopts a flattened boat conformation and the plane of the base of the boat forms a dihedral angle of 80.8 (2)° with the aromatic six-membered ring. The packing is stabilized by strong inter-molecular N-H⋯O(carbon-yl), O(hydrox-y)-H⋯O(carbon-yl) and weak intra-mole ...[more]

PMID: 22064645

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Dimethyl 2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate.

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