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4-Hydr-oxy-3-(1'-methyl-2-oxo-4'-phenyl-spiro-[indoline-3,2'-pyrrolidine]-3'-yl-carbon-yl)quinolin-2(1H)-one.

ABSTRACT: In the title compound, C(28)H(23)N(3)O(4), the dihedral angle between the quinoline and indole ring systems is 29.30?(5)°. The pyrrolidine ring adopts a twist conformation. An intra-molecular O-H?O hydrogen bond generates an S(6) ring motif. A weak intra-molecular C3-H3?O3 inter-action is also observed. In the crystal, mol-ecules are linked by two sets of N-H?O hydrogen bonds, forming centrosymmetric dimers containing two R(2) (2)(8) ring motifs. The dimers are linked via C-H?? inter-actions.

SUBMITTER: Revathi K

PROVIDER: S-EPMC2983794 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature

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4-Hydr-oxy-3-(1'-methyl-2-oxo-4'-phenyl-spiro-[indoline-3,2'-pyrrolidine]-3'-yl-carbon-yl)quinolin-2(1H)-one.

Revathi K K Sankaran M M Ramesh P P Mohan P S PS Ponnuswamy M N MN

Acta crystallographica. Section E, Structure reports online 20100327 Pt 4

In the title compound, C(28)H(23)N(3)O(4), the dihedral angle between the quinoline and indole ring systems is 29.30 (5)°. The pyrrolidine ring adopts a twist conformation. An intra-molecular O-H⋯O hydrogen bond generates an S(6) ring motif. A weak intra-molecular C3-H3⋯O3 inter-action is also observed. In the crystal, mol-ecules are linked by two sets of N-H⋯O hydrogen bonds, forming centrosymmetric dimers containing two R(2) (2)(8) ring motifs. The dimers are linked via C-H⋯π inter-actions. ...[more]

PMID: 21580756

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