Ontology highlight
ABSTRACT:
SUBMITTER: Chan KY
PROVIDER: S-EPMC2984613 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Molecular and biochemical parasitology 20100820 2
TbKif13-2, a member of the microtubule-depolymerising Kinesin-13 family was localised at the tip of the flagellum in Trypanosoma brucei. Its predicted activity suggested a role in the regulation of axonemal length. However, using gene deletion and overexpression of TbKif13-2 we show that, in procyclic T. brucei, this kinesin has only a very limited effect on flagellar length. Gene deletion resulted in no significant elongation of the flagellum and overexpression only slightly decreased flagellar ...[more]