Unknown

Dataset Information

0

The effect of midlife physical activity on cognitive function among older adults: AGES--Reykjavik Study.


ABSTRACT:

Background

There are few studies on the long-term associations of physical activity (PA) to cognition. Here, we examine the association of midlife PA to late-life cognitive function and dementia.

Methods

The sample consisted of a population-based cohort of men and women (born in 1907-1935) participating in the Age Gene/Environment Susceptibility-Reykjavik Study. The interval between the midlife ascertainment of PA and late-life cognitive function was 26 years. Composite scores of speed of processing, memory, and executive function were assessed with a battery of neuropsychological tests, and dementia was diagnosed according to international guidelines. There were 4,761 nondemented participants and 184 (3.7%) with a diagnosis of dementia, with complete data for the analysis.

Results

Among the participants, no midlife PA was reported by 68.8%, ? 5 hours PA by 26.5%, and >5 hours PA by 4.5%. Excluding participants with dementia compared with the no PA group, both PA groups had significantly faster speed of processing (? 5 hours, ? = .22; >5 hours, ? = .32, p trend < .0001), better memory (? 5 hours, ? = .15; >5 hours, ? = .18, p trend < .0001), and executive function (? 5 hours, ? = .09; >5 hours, ? = .18, p trend< .0001), after controlling for demographic and cardiovascular factors. The ? 5 hours PA group was significantly less likely to have dementia in late life (odds ratio: 0.6, 95% confidence interval: 0.40-0.88) after adjusting for confounders.

Conclusion

Midlife PA may contribute to maintenance of cognitive function and may reduce or delay the risk of late-life dementia.

SUBMITTER: Chang M 

PROVIDER: S-EPMC2990266 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

The effect of midlife physical activity on cognitive function among older adults: AGES--Reykjavik Study.

Chang Milan M   Jonsson Palmi V PV   Snaedal Jon J   Bjornsson Sigurbjorn S   Saczynski Jane S JS   Aspelund Thor T   Eiriksdottir Gudny G   Jonsdottir Maria K MK   Lopez Oscar L OL   Harris Tamara B TB   Gudnason Vilmundur V   Launer Lenore J LJ  

The journals of gerontology. Series A, Biological sciences and medical sciences 20100830 12


<h4>Background</h4>There are few studies on the long-term associations of physical activity (PA) to cognition. Here, we examine the association of midlife PA to late-life cognitive function and dementia.<h4>Methods</h4>The sample consisted of a population-based cohort of men and women (born in 1907-1935) participating in the Age Gene/Environment Susceptibility-Reykjavik Study. The interval between the midlife ascertainment of PA and late-life cognitive function was 26 years. Composite scores of  ...[more]

Similar Datasets

| S-EPMC5386007 | biostudies-literature
| S-EPMC4180488 | biostudies-literature
| S-EPMC5161659 | biostudies-literature
| S-EPMC5233910 | biostudies-literature
| S-EPMC5027639 | biostudies-literature
| S-EPMC9768066 | biostudies-literature
| S-EPMC10663528 | biostudies-literature
| S-EPMC8769503 | biostudies-literature
| S-EPMC5562508 | biostudies-other
| S-EPMC10137112 | biostudies-literature