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Pharmacogenetics of osteoporosis.


ABSTRACT: Osteoporosis is a complex bone disorder with a strong genetic basis. The genetics of osteoporosis encompasses two main areas: genetics of disease susceptibility and pharmacogenetics of drug response. The former has been widely studied in the past few decades, while the latter is still largely untouched. This review will provide an overview of the pharmacogenetics of osteoporosis, focusing on the major recent advances in the past two years.

SUBMITTER: Marini F 

PROVIDER: S-EPMC2990451 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature

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Pharmacogenetics of osteoporosis.

Marini Francesca F   Brandi Maria Luisa ML  

F1000 biology reports 20100819


Osteoporosis is a complex bone disorder with a strong genetic basis. The genetics of osteoporosis encompasses two main areas: genetics of disease susceptibility and pharmacogenetics of drug response. The former has been widely studied in the past few decades, while the latter is still largely untouched. This review will provide an overview of the pharmacogenetics of osteoporosis, focusing on the major recent advances in the past two years. ...[more]

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