Ontology highlight
ABSTRACT:
SUBMITTER: Nesmelova IV
PROVIDER: S-EPMC2991504 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Nesmelova Irina V IV Hackett Perry B PB
Advanced drug delivery reviews 20100706 12
DNA transposons are mobile DNA elements that can move from one DNA molecule to another and thereby deliver genetic information into human chromosomes in order to confer a new function or replace a defective gene. This process requires a transposase enzyme. During transposition DD[E/D]-transposases undergo a series of conformational changes. We summarize the structural features of DD[E/D]-transposases for which three-dimensional structures are available and that relate to transposases, which are ...[more]