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A supramolecular approach for preparation of size-controlled nanoparticles.


ABSTRACT: A supramolecular approach has been developed for the preparation of supramolecular nanoparticles (SNPs) with variable sizes (30-450 nm) from three different molecular building blocks using a cyclodextrin/adamantane recognition system. Positron emission tomography (PET) was employed to study the biodistribution and lymph node drainage of the SNPs in mice. The sizes of the SNPs affect their in vivo characteristics (see picture).

SUBMITTER: Wang H 

PROVIDER: S-EPMC2995451 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature

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A supramolecular approach for preparation of size-controlled nanoparticles.

Wang Hao H   Wang Shutao S   Su Helen H   Chen Kuan-Ju KJ   Armijo Amanda Lee AL   Lin Wei-Yu WY   Wang Yanju Y   Sun Jing J   Kamei Ken-ichiro K   Czernin Johannes J   Radu Caius G CG   Tseng Hsian-Rong HR  

Angewandte Chemie (International ed. in English) 20090101 24


A supramolecular approach has been developed for the preparation of supramolecular nanoparticles (SNPs) with variable sizes (30-450 nm) from three different molecular building blocks using a cyclodextrin/adamantane recognition system. Positron emission tomography (PET) was employed to study the biodistribution and lymph node drainage of the SNPs in mice. The sizes of the SNPs affect their in vivo characteristics (see picture). ...[more]

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