Ontology highlight
ABSTRACT:
SUBMITTER: Telleria J
PROVIDER: S-EPMC2996636 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Telleria Jenny J Biron David G DG Brizard Jean-Paul JP Demettre Edith E Séveno Martial M Barnabé Christian C Ayala Francisco J FJ Tibayrenc Michel M
Proceedings of the National Academy of Sciences of the United States of America 20101108 47
We performed a phylogenetic character mapping on 26 stocks of Trypanosoma cruzi, the parasite responsible for Chagas disease, and 2 stocks of the sister taxon T. cruzi marinkellei to test for possible associations between T. cruzi-subspecific phylogenetic diversity and levels of protein expression, as examined by proteomic analysis and mass spectrometry. We observed a high level of correlation (P < 10(-4)) between genetic distance, as established by multilocus enzyme electrophoresis, and proteom ...[more]