Ontology highlight
ABSTRACT:
SUBMITTER: Veetil JV
PROVIDER: S-EPMC2997158 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Veetil Jithesh V JV Jin Sha S Ye Kaiming K
Biosensors & bioelectronics 20100823 4
In vivo continuous glucose monitoring has posed a significant challenge to glucose sensor development due to the lack of reliable techniques that are non- or at least minimally-invasive. In this proof-of-concept study, we demonstrated the development of a new glucose sensor protein, AcGFP1-GBPcys-mCherry, and an optical sensor assembly, capable of generating quantifiable FRET (fluorescence resonance energy transfer) signals for glucose monitoring. Our experimental data showed that the engineered ...[more]