Ontology highlight
ABSTRACT:
SUBMITTER: Terenna CR
PROVIDER: S-EPMC2997722 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Terenna Courtney R CR Makushok Tatyana T Velve-Casquillas Guilhem G Baigl Damien D Chen Yong Y Bornens Michel M Paoletti Anne A Piel Matthieu M Tran Phong T PT
Current biology : CB 20081101 22
The cylindrical rod shape of the fission yeast Schizosaccharomyces pombe is organized and maintained by interactions between the microtubule, cell membrane, and actin cytoskeleton [1]. Mutations affecting any components in this pathway lead to bent, branched, or round cells [2]. In this context, the cytoskeleton controls cell polarity and thus dictates cell shape. Here, we use soft-lithography techniques to construct microfluidic channels to control cell shape. We show that when wild-type rod-sh ...[more]