Ontology highlight
ABSTRACT:
SUBMITTER: Haupt A
PROVIDER: S-EPMC5221626 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Molecular biology of the cell 20161116 1
Surface charges at the inner leaflet of the plasma membrane may contribute to regulate the surface recruitment of key signaling factors. Phosphatidylserine (PS) is an abundant charged lipid that may regulate charge distribution in different cell types. Here we characterize the subcellular distribution and function of PS in the rod-shaped, polarized fission yeast. We find that PS preferably accumulates at cell tips and defines a gradient of negative charges along the cell surface. This polarizati ...[more]