Ontology highlight
ABSTRACT:
SUBMITTER: York B
PROVIDER: S-EPMC2998129 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
York Brian B O'Malley Bert W BW
The Journal of biological chemistry 20101018 50
The three members of the p160 family of steroid receptor coactivators (SRC-1, SRC-2, and SRC-3) steer the functional output of numerous genetic programs and serve as pleiotropic rheostats for diverse physiological processes. Since their discovery ∼15 years ago, the extraordinary sum of examination of SRC function has shaped the foundation of our knowledge for the now 350+ coregulators that have been identified to date. In this perspective, we retrace our steps into the field of coregulators and ...[more]