Ontology highlight
ABSTRACT:
SUBMITTER: Stamp AL
PROVIDER: S-EPMC2998724 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Stamp Anna L AL Owen Paul P El Omari Kamel K Nichols Charles E CE Lockyer Michael M Lamb Heather K HK Charles Ian G IG Hawkins Alastair R AR Stammers David K DK
Protein science : a publication of the Protein Society 20101001 10
YcbL has been annotated as either a metallo-β-lactamase or glyoxalase II (GLX2), both members of the zinc metallohydrolase superfamily, that contains many enzymes with a diverse range of activities. Here, we report crystallographic and biochemical data for Salmonella enterica serovar Typhimurium YcbL that establishes it as GLX2, which differs in certain structural and functional properties compared with previously known examples. These features include the insertion of an α-helix after residue 8 ...[more]