Ontology highlight
ABSTRACT:
SUBMITTER: Stephenson N
PROVIDER: S-EPMC2999590 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Stephenson Nadine N Beckmann Lars L Chang-Claude Jenny J
Epidemiologic perspectives & innovations : EP+I 20101116
<h4>Background</h4>Standard logistic regression with or without stepwise selection has the disadvantage of not incorporating model uncertainty and the dependency of estimates on the underlying model into the final inference. We explore the use of a Bayes Model Averaging approach as an alternative to analyze the influence of genetic variants, environmental effects and their interactions on disease.<h4>Methods</h4>Logistic regression with and without stepwise selection and Bayes Model Averaging we ...[more]