Glutamatergic modulators: the future of treating mood disorders?
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ABSTRACT:
SUBMITTER: Zarate C
PROVIDER: S-EPMC3000412 | biostudies-literature | 2010 Sep-Oct
REPOSITORIES: biostudies-literature
Publications
Glutamatergic modulators: the future of treating mood disorders?
Zarate Carlos C Machado-Vieira Rodrigo R Henter Ioline I Ibrahim Lobna L Diazgranados Nancy N Salvadore Giacomo G
Harvard review of psychiatry 20100901 5
Mood disorders such as bipolar disorder and major depressive disorder are common, chronic, and recurrent conditions affecting millions of individuals worldwide. Existing antidepressants and mood stabilizers used to treat these disorders are insufficient for many. Patients continue to have low remission rates, delayed onset of action, residual subsyndromal symptoms, and relapses. New therapeutic agents able to exert faster and sustained antidepressant or mood-stabilizing effects are urgently need ...[more]
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