A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN.
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ABSTRACT:
SUBMITTER: Garber KC
PROVIDER: S-EPMC3005762 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Publications
A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN.
Garber Kathleen C A KC Wangkanont Kittikhun K Carlson Erin E EE Kiessling Laura L LL
Chemical communications (Cambridge, England) 20100818 36
Shikimic acid can be transformed into monovalent and multivalent glycomimetics that target different members of the C-type lectin class, including DC-SIGN, a dendritic cell lectin that facilitates HIV transmission. ...[more]
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