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1-Bromo-2-(10?-dihydro-artemisin-oxy)ethane.

ABSTRACT: The title compound, C(17)H(27)BrO(5), DEB, is a derivative of artemisinin which is used in malara therapy. The OR-group at C12 is cis to the CH(3)-group at C11 and axially oriented on ring D which has a chair conformation. The crystal packing is stabilized by several weak inter-molecular C-H?O inter-actions, which combine to form a C-H-O bonded network parallel to (001).

SUBMITTER: Lombard MC

PROVIDER: S-EPMC3007557 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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1-Bromo-2-(10β-dihydro-artemisin-oxy)ethane.

Lombard Marli C MC Fernandes Manuel A MA Breytenbach Jaco C JC N'da David D DD

Acta crystallographica. Section E, Structure reports online 20100731 Pt 8

The title compound, C(17)H(27)BrO(5), DEB, is a derivative of artemisinin which is used in malara therapy. The OR-group at C12 is cis to the CH(3)-group at C11 and axially oriented on ring D which has a chair conformation. The crystal packing is stabilized by several weak inter-molecular C-H⋯O inter-actions, which combine to form a C-H-O bonded network parallel to (001). ...[more]

PMID: 21588460

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