Ontology highlight
ABSTRACT:
SUBMITTER: Lassmann T
PROVIDER: S-EPMC3008642 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Lassmann Timo T Hayashizaki Yoshihide Y Daub Carsten O CO
Bioinformatics (Oxford, England) 20101118 1
<h4>Motivation</h4>The sequence alignment/map format (SAM) is a commonly used format to store the alignments between millions of short reads and a reference genome. Often certain positions within the reads are inherently more likely to contain errors due to the protocols used to prepare the samples. Such biases can have adverse effects on both mapping rate and accuracy. To understand the relationship between potential protocol biases and poor mapping we wrote SAMstat, a simple C program plotting ...[more]