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Ethyl 2-{(2Z)-2-[(1-naphthyl-sulfon-yl)imino]-2,3-dihydro-1,3-thia-zol-4-yl}acetate monohydrate.

ABSTRACT: The title compound, C(17)H(16)N(2)O(4)S(2)·H(2)O, is of inter-est with respect to its anti-diabetic and anti-obesity activity. In the crystal, the packing is stabilized by three cooperative inter-actions: offset ?-? inter-actions [centroid-centroid distance = 3.604?(2)?Å], as well as C-H?O and O-H?O hydrogen bonds. N-H?O inter-actions also occur.

SUBMITTER: Navarrete-Vazquez G

PROVIDER: S-EPMC3009274 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

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Ethyl 2-{(2Z)-2-[(1-naphthyl-sulfon-yl)imino]-2,3-dihydro-1,3-thia-zol-4-yl}acetate monohydrate.

Navarrete-Vázquez Gabriel G Morales-Vilchis Guadalupe G Estrada-Soto Samuel S Estrada-Soto Samuel S Rodríguez-López Verónica V Rodríguez-López Verónica V Rodríguez-López Verónica V Tlahuext Hugo H

Acta crystallographica. Section E, Structure reports online 20101009 Pt 11

The title compound, C(17)H(16)N(2)O(4)S(2)·H(2)O, is of inter-est with respect to its anti-diabetic and anti-obesity activity. In the crystal, the packing is stabilized by three cooperative inter-actions: offset π-π inter-actions [centroid-centroid distance = 3.604 (2) Å], as well as C-H⋯O and O-H⋯O hydrogen bonds. N-H⋯O inter-actions also occur. ...[more]

PMID: 21588949

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