Ontology highlight
ABSTRACT:
SUBMITTER: Gotoh M
PROVIDER: S-EPMC3010700 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Gotoh Masahiro M Arai Eri E Wakai-Ushijima Saori S Hiraoka Nobuyoshi N Kosuge Tomoo T Hosoda Fumie F Shibata Tatsuhiro T Kondo Tadashi T Yokoi Sana S Imoto Issei I Inazawa Johji J Kanai Yae Y
Journal of biomedicine & biotechnology 20101221
To establish diagnostic criteria for ductal adenocarcinomas of the pancreas (PCs), bacterial artificial chromosome (BAC) array-based methylated CpG island amplification was performed using 139 tissue samples. Twelve BAC clones, for which DNA methylation status was able to discriminate cancerous tissue (T) from noncancerous pancreatic tissue in the learning cohort with a specificity of 100%, were identified. Using criteria that combined the 12 BAC clones, T-samples were diagnosed as cancers with ...[more]