Ontology highlight
ABSTRACT:
SUBMITTER: Zhao B
PROVIDER: S-EPMC3012551 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Zhao Baofeng B Chun Changzoon C Liu Zhong Z Horswill Mark A MA Pramanik Kallal K Wilkinson George A GA Ramchandran Ramani R Miao Robert Q RQ
Blood 20100902 24
Our previous work has shown that axon guidance gene family Nogo-B and its receptor (NgBR) are essential for chemotaxis and morphogenesis of endothelial cells in vitro. To investigate NogoB-NgBR function in vivo, we cloned the zebrafish ortholog of both genes and studied loss of function in vivo using morpholino antisense technology. Zebrafish ortholog of Nogo-B is expressed in somite while expression of zebrafish NgBR is localized in intersomitic vessel (ISV) and axial dorsal aorta during embryo ...[more]