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Pyrosequencing of the genital microbiotas of HIV-seropositive and -seronegative women reveals Lactobacillus iners as the predominant Lactobacillus Species.


ABSTRACT: The species of vaginal lactobacilli in HIV-seropositive and -seronegative women were determined by 16S gene pyrosequencing. Lactobacillus iners sequences were the predominant lactobacillus sequences in 66% of HIV(+) women and 90% of HIV(-) women. This has implications for resistance of HIV(+) and HIV(-) women to genital colonization by pathogenic organisms.

SUBMITTER: Spear GT 

PROVIDER: S-EPMC3019699 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

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Pyrosequencing of the genital microbiotas of HIV-seropositive and -seronegative women reveals Lactobacillus iners as the predominant Lactobacillus Species.

Spear Gregory T GT   Gilbert Douglas D   Landay Alan L AL   Zariffard Reza R   French Audrey L AL   Patel Pranjal P   Gillevet Patrick M PM  

Applied and environmental microbiology 20101112 1


The species of vaginal lactobacilli in HIV-seropositive and -seronegative women were determined by 16S gene pyrosequencing. Lactobacillus iners sequences were the predominant lactobacillus sequences in 66% of HIV(+) women and 90% of HIV(-) women. This has implications for resistance of HIV(+) and HIV(-) women to genital colonization by pathogenic organisms. ...[more]

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