Ontology highlight
ABSTRACT:
SUBMITTER: Tuzmen C
PROVIDER: S-EPMC3026835 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
PloS one 20110125 1
The nonlocal nature of the protein-ligand binding problem is investigated via the Gaussian Network Model with which the residues lying along interaction pathways in a protein and the residues at the binding site are predicted. The predictions of the binding site residues are verified by using several benchmark systems where the topology of the unbound protein and the bound protein-ligand complex are known. Predictions are made on the unbound protein. Agreement of results with the bound complexes ...[more]