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Value encoding in single neurons in the human amygdala during decision making.

ABSTRACT: A growing consensus suggests that the brain makes simple choices by assigning values to the stimuli under consideration and then comparing these values to make a decision. However, the network involved in computing the values has not yet been fully characterized. Here, we investigated whether the human amygdala plays a role in the computation of stimulus values at the time of decision making. We recorded single neuron activity from the amygdala of awake patients while they made simple purchase decisions over food items. We found 16 amygdala neurons, located primarily in the basolateral nucleus that responded linearly to the values assigned to individual items.

SUBMITTER: Jenison RL

PROVIDER: S-EPMC3028386 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

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Value encoding in single neurons in the human amygdala during decision making.

Jenison Rick L RL Rangel Antonio A Oya Hiroyuki H Kawasaki Hiroto H Howard Matthew A MA

The Journal of neuroscience : the official journal of the Society for Neuroscience 20110101 1

A growing consensus suggests that the brain makes simple choices by assigning values to the stimuli under consideration and then comparing these values to make a decision. However, the network involved in computing the values has not yet been fully characterized. Here, we investigated whether the human amygdala plays a role in the computation of stimulus values at the time of decision making. We recorded single neuron activity from the amygdala of awake patients while they made simple purchase d ...[more]

PMID: 21209219

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