Ontology highlight
ABSTRACT:
SUBMITTER: Weber PW
PROVIDER: S-EPMC3030251 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Weber Paul W PW Howle Laurens E LE Murray Mark M MM Corless Joseph M JM
Biophysical journal 20110201 3
When radiolabeled precursors and autoradiography are used to investigate turnover of protein components in photoreceptive cone outer segments (COSs), the labeled components--primarily visual pigment molecules (opsins)--are diffusely distributed along the COS. To further assess this COS labeling pattern, we derive a simplified mass-transfer model for quantifying the contributions of advective and diffusive mechanisms to the distribution of opsins within COSs of the frog retina. Two opsin-containi ...[more]