Ontology highlight
ABSTRACT:
SUBMITTER: Kawanaka N
PROVIDER: S-EPMC3030990 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Kawanaka Norikuni N Taylor Andrew W AW
Journal of neuroimmunology 20101020 1-2
The functionality of immune cells is manipulated within the ocular microenvironment to protect the sensitive and non-regenerating light-gathering tissue from the collateral damage of inflammation. This is mediated partly by the constitutive presence of immunomodulating neuropeptides. Treating primary resting macrophages with soluble factors produced by the posterior eye induced co-expression of Arginase1 and NOS2. The neuropeptides alpha-melanocyte stimulating hormone and Neuropeptide Y alternat ...[more]