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[3+2] cycloadditions of aryl cyclopropyl ketones by visible light photocatalysis.

ABSTRACT: We report a new method for the formal [3+2] reaction of aryl cyclopropyl ketones with olefins to generate highly substituted cyclopentane ring systems. The key initiation step in this process is the one-electron reduction of the ketone to the corresponding radical anion, which is accomplished using a photocatalytic system comprising Ru(bpy)(3)(2+), La(OTf)(3), and TMEDA.

SUBMITTER: Lu Z

PROVIDER: S-EPMC3033486 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature

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[3+2] cycloadditions of aryl cyclopropyl ketones by visible light photocatalysis.

Lu Zhan Z Shen Meihua M Yoon Tehshik P TP

Journal of the American Chemical Society 20110107 5

We report a new method for the formal [3+2] reaction of aryl cyclopropyl ketones with olefins to generate highly substituted cyclopentane ring systems. The key initiation step in this process is the one-electron reduction of the ketone to the corresponding radical anion, which is accomplished using a photocatalytic system comprising Ru(bpy)(3)(2+), La(OTf)(3), and TMEDA. ...[more]

PMID: 21214249

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