A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression.

ABSTRACT:

Background

Obesity is associated with clinical depression among women. However, depressed women are often excluded from weight loss trials.

Purpose

This study examined treatment outcomes among women with comorbid obesity and depression.

Methods

Two hundred three (203) women were randomized to behavioral weight loss (n = 102) or behavioral weight loss combined with cognitive-behavioral depression management (n = 101).

Results

Average participant age was 52 years; mean baseline body mass index was 39 kg/m(2). Mean Patient Health Questionnaire and Hopkins Symptom Checklist (SCL-20) scores indicated moderate to severe baseline depression. Weight loss and SCL-20 changes did not differ between groups at 6 or 12 months in intent-to-treat analyses (p = 0.26 and 0.55 fo

SUBMITTER: Linde JA 

PROVIDER: S-EPMC3033656 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature