Randomized controlled trial of behavioral treatment for comorbid obesity and depression in women: the Be Active Trial.

ABSTRACT:

Objective

Depression is associated with increased risk for obesity and worse weight loss treatment outcomes. The purpose of the present study was to test the hypothesis that delivering evidence-based behavior therapy for depression before a lifestyle weight loss intervention improves both weight loss and depression.

Design

In a randomized controlled trial, obese women with major depressive disorder (N=161, mean age=45.9 (s.d.: 10.8) years) were randomized to brief behavior therapy for depression treatment followed by a lifestyle intervention (BA) or a lifestyle intervention only (LI). Follow-up occurred at 6 and 12 months. Main outcome measures included weight loss and depression symptoms.

Results

Intention-to-treat analyses revealed both conditions lost significant w

SUBMITTER: Pagoto S 

PROVIDER: S-EPMC3675166 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature