Ontology highlight
ABSTRACT:
SUBMITTER: Dos Santos A
PROVIDER: S-EPMC3035364 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Dos Santos Alexandre A Thiers Valérie V Sar Sokhavuth S Derian Nicolas N Bensalem Noura N Yilmaz Funda F Bralet Marie-Pierre MP Ducot Béatrice B Bréchot Christian C Demaugre France F
Proteomics. Clinical applications 20070511 6
Hepatocellular carcinoma (HCC) is a major cause of cancer worldwide. Proteomic studies provide opportunities to uncover targets for the diagnosis and treatment of this disease. However, in HCC developing in a setting of cirrhosis, the detection of proteome alterations may be hampered by the increased cellular heterogeneity of tissue when analysing global liver homogenates. The aim of this study was to evaluate whether the identification of proteome alterations in these HCC cases was improved whe ...[more]