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Clinical, genetic, and pathological features of male pseudohermaphroditism in dog.

ABSTRACT: Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male pseudohermaphrodite (MPH) condition.

SUBMITTER: Bigliardi E 

PROVIDER: S-EPMC3036612 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

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Clinical, genetic, and pathological features of male pseudohermaphroditism in dog.

Bigliardi Enrico E   Parma Pietro P   Peressotti Paolo P   De Lorenzi Lisa L   Wohlsein Peter P   Passeri Benedetta B   Jottini Stefano S   Cantoni Anna Maria AM  

Reproductive biology and endocrinology : RB&E 20110121

Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male  ...[more]

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