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Microfilaruria by Dirofilaria immitis in a dog: a rare clinical pathological finding.


ABSTRACT: A 6-year-old Labrador with history of hyperpnea, respiratory distress, ascites and paraparesis, presented Dirofilaria immitis microfilariae in the blood smear, cytology of the abdominal fluid and urine. The positive samples were confirmed by multiplex-PCR (COI gene) and sequencing, and presented 98% homology to D. immitis (GenBank accession nos. KC107805.1, EU159111.1, EU163945.1, DQ358815.1, and AJ537512-1). Based on the presented results and the physiopathology of the heartworm disease, molecular techniques may be helpful and accurate in the diagnosis of the disease in vertebrates, and microfilaruria, even uncommon, should be considered on a renal failure evaluation.

SUBMITTER: Monobe MM 

PROVIDER: S-EPMC5555937 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature

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Microfilaruria by <i>Dirofilaria immitis</i> in a dog: a rare clinical pathological finding.

Monobe Marina Mitie MM   da Silva Rodrigo Costa RC   Araujo Junior João Pessoa JP   Takahira Regina Kiomi RK  

Journal of parasitic diseases : official organ of the Indian Society for Parasitology 20170218 3


A 6-year-old Labrador with history of hyperpnea, respiratory distress, ascites and paraparesis, presented <i>Dirofilaria immitis</i> microfilariae in the blood smear, cytology of the abdominal fluid and urine. The positive samples were confirmed by multiplex-PCR (COI gene) and sequencing, and presented 98% homology to <i>D. immitis</i> (GenBank accession nos. KC107805.1, EU159111.1, EU163945.1, DQ358815.1, and AJ537512-1). Based on the presented results and the physiopathology of the heartworm d  ...[more]

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