Ontology highlight
ABSTRACT:
SUBMITTER: Lamarque M
PROVIDER: S-EPMC3037350 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Lamarque Mauld M Besteiro Sébastien S Papoin Julien J Roques Magali M Vulliez-Le Normand Brigitte B Morlon-Guyot Juliette J Dubremetz Jean-François JF Fauquenoy Sylvain S Tomavo Stanislas S Faber Bart W BW Kocken Clemens H CH Thomas Alan W AW Boulanger Martin J MJ Bentley Graham A GA Lebrun Maryse M
PLoS pathogens 20110210 2
Obligate intracellular Apicomplexa parasites share a unique invasion mechanism involving a tight interaction between the host cell and the parasite surfaces called the moving junction (MJ). The MJ, which is the anchoring structure for the invasion process, is formed by secretion of a macromolecular complex (RON2/4/5/8), derived from secretory organelles called rhoptries, into the host cell membrane. AMA1, a protein secreted from micronemes and associated with the parasite surface during invasion ...[more]