Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez-Martin D
PROVIDER: S-EPMC3037632 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Sánchez-Martín David D Cuesta Angel M AM Fogal Valentina V Ruoslahti Erkki E Alvarez-Vallina Luis L
The Journal of biological chemistry 20101214 7
Tumor-associated cell surface antigens and tumor-associated vascular markers have been used as a target for cancer intervention strategies. However, both types of targets have limitations due to accessibility, low and/or heterogeneous expression, and presence of tumor-associated serum antigen. It has been previously reported that a mitochondrial/cell surface protein, p32/gC1qR, is the receptor for a tumor-homing peptide, LyP-1, which specifically recognizes an epitope in tumor cells, tumor lymph ...[more]