Ontology highlight
ABSTRACT:
SUBMITTER: Villa-Garcia MJ
PROVIDER: S-EPMC3037835 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Villa-García Manuel J MJ Choi Myung Sun MS Hinz Flora I FI Gaspar María L ML Jesch Stephen A SA Henry Susan A SA
Molecular genetics and genomics : MGG 20101207 2
Inositol auxotrophy (Ino(-) phenotype) in budding yeast has classically been associated with misregulation of INO1 and other genes involved in lipid metabolism. To identify all non-essential yeast genes that are necessary for growth in the absence of inositol, we carried out a genome-wide phenotypic screening for deletion mutants exhibiting Ino(-) phenotypes under one or more growth conditions. We report the identification of 419 genes, including 385 genes not previously reported, which exhibit ...[more]