A novel role of periostin in postnatal tooth formation and mineralization.
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ABSTRACT:
SUBMITTER: Ma D
PROVIDER: S-EPMC3039381 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Publications
A novel role of periostin in postnatal tooth formation and mineralization.
Ma Dedong D Zhang Rong R Sun Yao Y Rios Hector F HF Haruyama Naoto N Han Xianglong X Kulkarni Ashok B AB Qin Chunlin C Feng Jian Q JQ
The Journal of biological chemistry 20101203 6
Periostin plays multiple functions during development. Our previous work showed a critical role of this disulfide-linked cell adhesion protein in maintenance of periodontium integrity in response to occlusal load. In this study, we attempted to address whether this mechanical response molecule played a direct role in postnatal tooth development. Our key findings are 1) periostin is expressed in preodontoblasts, and odontoblasts; and the periostin-null incisor displayed a massive increase in dent ...[more]
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