Molecular genetics and clinical applications for RH.
Ontology highlight
ABSTRACT:
SUBMITTER: Flegel WA
PROVIDER: S-EPMC3042511 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Publications
Molecular genetics and clinical applications for RH.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20110128 1
Rhesus is the clinically most important protein-based blood group system. It represents the largest number of antigens and the most complex genetics of the 30 known blood group systems. The RHD and RHCE genes are strongly homologous. Some genetic complexity is explained by their close chromosomal proximity and unusual orientation, with their tail ends facing each other. The antigens are expressed by the RhD and the RhCE proteins. Rhesus exemplifies the correlation of genotype and phenotype, faci ...[more]
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