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Evidence of a recombinant wild-type human astrovirus strain from a Kenyan child with gastroenteritis.

ABSTRACT: A human astrovirus (HAstV) strain from Kenya was characterized by nucleotide sequence analysis. Sequences from open reading frame 1a (ORF1a) clustered with genotype 6/7, those from ORF1b clustered with genotype 3, and those from ORF2 clustered with genotype 2. A recombination point in the ORF1b-ORF2 junction was identified, with a second possible recombination point within the ORF1a region.

SUBMITTER: Wolfaardt M

PROVIDER: S-EPMC3043485 | biostudies-literature | 2011 Feb

REPOSITORIES: biostudies-literature

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Evidence of a recombinant wild-type human astrovirus strain from a Kenyan child with gastroenteritis.

Wolfaardt Marianne M Kiulia Nicholas M NM Mwenda Jason M JM Taylor Maureen B MB

Journal of clinical microbiology 20101124 2

A human astrovirus (HAstV) strain from Kenya was characterized by nucleotide sequence analysis. Sequences from open reading frame 1a (ORF1a) clustered with genotype 6/7, those from ORF1b clustered with genotype 3, and those from ORF2 clustered with genotype 2. A recombination point in the ORF1b-ORF2 junction was identified, with a second possible recombination point within the ORF1a region. ...[more]

PMID: 21106800

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